Ace crimefighter Joe Saeba, a.k.a. City Hunter is at least as interested in 'nookie' as he is in busting the bad guys, so when he's not trying to score with one of his legion of female admirers, he's getting his skull battered by Kaori, his jealously protective sidekick and would-be girlfriend. Joe is a lecherous, egotistical nut case who never gets the girl. The only time he is serious is when he has his 357 Magnum out. City Hunter's latest object of desire is Amy Makaze, a damsel-in-distress whose brother - now known only as "The Professor" - has turned from military heroism to ruthless terrorism and plans to destroy several major Japanese cities in revenge against the government that betrayed him. It's up to City Hunter to foil the madman's scheme before its too late.