Blue Gender (Vol. 1)

Yuji, a high school teenager, discovers that he has a new and incurable virus. With life looking very bleak, he's left only one option - hope that the future may hold a cure. With his decision made, he opts to undergo artificial hibernation. He's awakened 22 years later to find that Earth has been conquered by the Blue - monstrous, insectlike aliens. Yuji is rescued by tough-as-railroad-spikes mecha pilot Marlene Angel, who serves in an elite Sleeper Recovery Team from the satellite Second Earth. Yuji is apparently a valuable asset in the struggle against the Blue, despite his illness.