Black Jack is a master surgeon who possesses impeccable skills, enabling him to perform operations that are impossible for even the finest surgeons. He now is faced with his most difficult task to date and must challenge the limits of medical science... before it's too late! Black Jack is called in to develop a cure for a mysterious disease that's ravaging 'Super Humans' - people of no discernible ability who suddenly burst onto the scene as stars in sports or the arts. The key to the emergence of the Super Humans and the disease is pharmaceutical heiress and surgeon Jo Carol. Sometimes as allies, sometimes as enemies, Black Jack and Jo Carol uncover the nature of the disease - and the program of human experimentation that produced it.