The mystical book, 'The Universe of the Four Gods', was finally closed when Miaka made her last wish, or so everyone had thought. But old enemies have returned from beyond the grave to claim their revenge, and this time it is Tamahome who is drawn into the book to become one of the Seiryu Seven! Now Yui, Keisuke, and Tetsuya must discover how the book was opened, while Miaka and Tamahome, now known as Taka, race to relearn how to survive in the Mysterious Play!